MIT Researchers Have Success Treating Alzheimer's in Mice with SIRT1 Gene

Researchers at the Massachusetts Institute of Technology had recent success treating a model version of Alzheimer's disease in mice.

Alzheimer's disease is a neurodegenerative disorder that affects up to 1 in 3 adults who reach the age of 80.

In a recent study published in the Journal Cell, MIT scientists indicate that they found a way to found a way to "dramatically reduce the erosion of memory and learning ability in mice with a version of Alzheimer's disease."

The results are attributable to working with the SIRT1 gene in mice brains.

The SIRT1 gene governs production of surtuin one proteins. 

SIRT1 is often referred to as the longevity gene.  Resveratrol and calorie restriction diets are intended to activate the SIRT1 or longevity gene.

According to an article in the Wall Street Journal:

"This is the first demonstration that the SIRT1 pathway can mitigate Alzheimer's," said Leonard Guarente, a biologist at MIT and the lead author of the study"

 

Source: Wall Street Journal

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