David Sinclair is Professor of Pathology at the Harvard Medical School.
Professor Sinclair presented some of his research at a recent conference sponsored by the International Longevity Center.
The research suggests that longevity genes can be leveraged to activate the human body's natural repair mechanisms and enhance longevity.
In particular, Sirtuins are proteins responsible for the positive aging effects that accompany caloric restriction. Professor Sinclair and his team of researchers are working on developing a drug that simulates the positive effects of caloric restriction:
Caloric restriction — eating 20 to 40 per cent fewer calories than normal — has been found to slow the aging process, he says, and that, in turn, reduces age-related diseases such as cancer, heart disease, osteoporosis and neurodegeneration.
Sinclair's team has found that proteins called Sirtuins are responsible for this delay, and they're working to develop a drug that could have the same effect without the stringent diet requirements of caloric restriction.
Source: Montreal Gazette
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